What is Huntington’s disease?

Huntington’s disease is a genetic, neurodegenerative disease with a devastating impact on individuals and entire families. Despite knowing the exact cause of Huntington’s disease since 1993, there still remains much unknown about this complex brain disease.

In this animation, Lauren Byrne, a Research Fellow at the UCL Huntington’s Disease Centre shares her personal experience with Huntington’s. She takes us inside the brain to explore the mechanism of this disease leading to the cognitive, behavioural and motor symptoms in Huntington’s.

This is a Roche video developed in collaboration with Ed Wild, also from UCL Huntington’s Disease Centre, George Yohrling from the Huntington’s Disease Society of America, and Roger and Brenda Wylie, a family living with Huntington’s disease.

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Comment (0)

  1. What about the relationship of Huntington's disease and neurotoxins like aluminum, acetaminophen, flouride, mercury, lead…etc… or even the correlation between the gut microbiome and the countless toxins found in processed foods like GMOs, pesticides, food additives, colorings, synthetic vitamins, antibiotics, neurotoxic psychiatric medications being taken while pregnant, the neurotoxins found in vaccines…. or the relationship with vitamin deficiencies like fat soluble vitamins A, D, and K2? Or the Omega-3 deficiencies in the diet?
    What if changing the "chemical, emotional and environmental stressors" played a major role in the gene expression?
    What about cholesterol deficient dietary pregnant women along with a lack of fat soluble vitamins while pregnant? Our brains need cholesterol and healthy fats like Omega 3 to properly form and mature?

    Have you studied any of these as possible solutions?

  2. I’ve missed out on time with my dad because he suffered from this but if anyone’s family member suffered from this disease don’t look at what is to come look at what happened

  3. I feel very fortunate that my mother doesn't carry the gene for it. Watching my grandmother's siblings and my cousins suffer has been awful.

    Side note, the side of my family who carries Huntington's disease emigrated to the U.S. from northern Ireland. I just thought that was interesting.

  4. My father has it and I was tested not too long ago and the results terrified me. I'm 36 years old and not looking forward to this taking over my mind and body as I get older.

  5. Heat-shock Proteins may be a key focus in the understatement of htt. HSP70 is a chaperon and sometimes will not recognize the htt protein meaning if we can use CRISPR to modify this gene we can and will understand this gene and find medical intervention

  6. You can seizures and spells that can be a hard time to get rid off although it can be cured with intense bots of the resumes of physical therapy but it’s if you are near. A good hospital for the future and for the future of disease you can get better over time

  7. I just wanted to say thank you, I started looking into this after Huntington’s took my twin sisters life at the age 21 and a half….you’re video helped me better understand the disease that took my sisters life…..honestly to this day I have never been to the doctors to see if I had it myself mainly for being to scared to know if I have it….but trying to build up the courage to hopefully go in for the test

  8. Just lost my father-in-law at age 48 to this disease. Due to the lack of study we were not able to get him help in time and I am scared my husband has the gene.

  9. Huntington, Virginia , 2021 "Nice and creative Videos,I can see A lot of thought has been put into the content and editing of the video, This is really my favorite channel.:) .🌴🌴🌴excellent 👍👌👍👌👍 🌴🌴🌴 🌴🌴🌴 🌴🌴🌴 🌴🌴🌴.

  10. Thank you for this great information!
    We have HD in my family and I am going to get myself testet in the comming weeks. This video gives a great explenation of the disease and how Forms.

  11. hello .
    I am about to graduate from medical school how can i be part of these disease researchs or pursue in advance studies like you a videoabout such guide will be highly appreciated thank you

  12. My husband has HD. He was in the clinical trial which recently ended abruptly. It is heartbreaking to watch him decline. Thank you for this video and your studies.

  13. Today is the first time I've ever heard of this disease. Filipinos might get diabetes but not Huntington's disease, M.S., skin cancer, osteoporosis, or hemophilia

  14. Thanks for making this beautiful video with an excellent explanation, I am going to start my research end of this year in this field of area (HD).

  15. Add copper sulfate, DMSO will help. I believe in certain races need more of certain minerals and vitamins because of genetic dispositions. But is a real disposition or lack of certain diet or exposure to chemicals in the work or home environment?

  16. mai sab ko yhi kkehna chauhaga , ke english medicine shod ke ayurveda ki taraf dhyaan do,, agr jad se thik hona chahte ho to,, maine is disease ko Planet Ayurvda ki help se thik kiya hai,, jo ki ek ayurvedic health care centre hai ,, aap search karo iske baare me, and apne health issue ko thik karo jad se

  17. I would bet a big burrito that this is the cause of US Rep Paul Gosar's (R-AZ) strange body movements, vocal irregularities & changes in personality since he left his dental career to enter politics. IF I am correct, his constituents really NEED TO KNOW, because HD affects the brain/mind processes as well as the body.

  18. My grandmother had it and died because of the disease.My aunt also unfortunately has this horrible disease.It skipped my mother who is older than my aunt and my uncle,who is younger then my aunt.I hope that one day they can cure this horrible disease.Prayers goes out to all that has this and their familys. 🙏🙏❤❤

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